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Lung function (FVC) and waist to hip ratio adjusted for BMI

UQCC1 · rs2425059

What the study found

Who was studied up to 100,285 Chinese ancestry individuals; replicated in up to 457,756 European ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 2 × 10−14.

Where it sits Chromosome 20, band 20q11.22 — in an intron of UQCC1.

What each result means

C/C No copy of the version the research linked to Lung function (FVC) and waist to hip ratio adjusted for BMI. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Lung function (FVC) and waist to hip ratio adjusted for BMI. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Lung function (FVC) and waist to hip ratio adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2425059

What is rs2425059?

rs2425059 is a single position in the genome, in or near the UQCC1 gene. Published research associates it with lung function (fvc) and waist to hip ratio adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2425059 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2425059 come from?

GWAS Catalog, The European respiratory journal 2021, PMID:33766948. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lung function (FVC) and waist to hip ratio adjusted for BMI (rs2425059). MyGeneLog™. https://www.mygenelog.com/variants/rs2425059

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