Standard

Brown vs. black hair color

PIGU · rs2424995

Where this position leads

Condition: Hair Color

rs2424995 Condition: Hair Color Hair Color Condition rs2424995 rs2424995 PIGU

What the study found

Who was studied 269,394 British ancestry brown hair individuals, 14,526 British ancestry black hair individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 1 × 10−65.

How common The A allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 20, band 20q11.22 — in an intron of PIGU.

What each result means

A/A Two copies of the version the research linked to Brown vs. black hair color. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Brown vs. black hair color. That is a smaller link than two copies.
T/T No copy of the version the research linked to Brown vs. black hair color. This is the starting point the study compared everyone against.
Source

Questions about rs2424995

What is rs2424995?

rs2424995 is a single position in the genome, in or near the PIGU gene. Published research associates it with brown vs. black hair color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2424995 linked to?

On MyGeneLog this position is linked to Hair Color. The research behind each link, and its sources, are set out on that condition page.

Does having rs2424995 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2424995 come from?

GWAS Catalog, Nature communications 2018, PMID:30531825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Brown vs. black hair color (rs2424995). MyGeneLog™. https://www.mygenelog.com/variants/rs2424995

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