2 411217323121Reads by AI crawlersClaude1ChatGPT2Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot3Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others21Total41Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 5,912 European ancestry cases, 181,740 European ancestry controls.
The effect
Each copy of the T allele carried 1.28 times the odds of Non-melanoma skin cancer (95% confidence interval 1.2-1.37); p = 8 × 10−13.
Where it sits Chromosome 20, band 20q11.21 — in an intron of BPIFB4.
What each result means
C/CNo copy of the version the research linked to Non-melanoma skin cancer. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Non-melanoma skin cancer. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Non-melanoma skin cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2018 · PMID 29739929 · open access
Questions about rs2424952
What is rs2424952?
rs2424952 is a single position in the genome, in or near the BPIFB4 gene. Published research associates it with non-melanoma skin cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2424952 linked to?
On MyGeneLog this position is linked to Sun Sensitivity, Freckling and Skin Cancer Risk. The research behind each link, and its sources, are set out on that condition page.
Does having rs2424952 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2424952 come from?
GWAS Catalog, Nat Commun 2018, PMID:29739929. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 411217323121Reads by AI crawlersClaude1ChatGPT2Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot3Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others21Total41Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Non-melanoma skin cancer (rs2424952). MyGeneLog™. https://www.mygenelog.com/variants/rs2424952