3 5142235222227Reads by AI crawlersClaude4ChatGPT2Google · Gemini2Perplexity3Meta AI5Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others27Total51Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,098 East Asian ancestry cases, 5,749 East Asian ancestry controls; replicated in 5,358 East Asian ancestry cases, 5,922 East Asian ancestry controls, 26,060 European ancestry individuals.
The effect
Each copy of the C allele carried 1.14 times the odds of Colorectal cancer (95% confidence interval 1.08-1.19); p = 2 × 10−7.
How common The C allele had a frequency of about 30% in the people studied.
Where it sits Chromosome 20, band 20p12.3 — inside SRSF10P2.
What each result means
C/CTwo copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs2423279
What is rs2423279?
rs2423279 is a single position in the genome, in or near the PLCB1 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2423279 linked to?
On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs2423279?
Subjects that appear in the title or abstract of the same papers as this rsID include alcohol and the flush (1 papers), blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs2423279 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2423279 come from?
GWAS Catalog, Nat Genet 2012, PMID:23263487. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 5142235222227Reads by AI crawlersClaude4ChatGPT2Google · Gemini2Perplexity3Meta AI5Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others27Total51Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Colorectal cancer (rs2423279). MyGeneLog™. https://www.mygenelog.com/variants/rs2423279