Sensitive

Plasma X-21441 levels in chronic kidney disease

SLCO1B3-SLCO1B7 · rs2417888

What the study found

Who was studied 4,051 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.256 lower (95% confidence interval 0.2-0.31); p = 6 × 10−18.

How common The T allele had a frequency of about 16% in the people studied.

Where it sits Chromosome 12, band 12p12.2 — in an intron of SLCO1B3-SLCO1B7.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Plasma X-21441 levels in chronic kidney disease — no copies of the reported risk allele.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Plasma X-21441 levels in chronic kidney disease.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Plasma X-21441 levels in chronic kidney disease compared to the general population.
Source

Questions about rs2417888

What is rs2417888?

rs2417888 is a single position in the genome, in or near the SLCO1B3-SLCO1B7 gene. Published research associates it with plasma x-21441 levels in chronic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2417888 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2417888 come from?

GWAS Catalog, Nature genetics 2023, PMID:37277652. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Plasma X-21441 levels in chronic kidney disease (rs2417888). MyGeneLog™. https://www.mygenelog.com/variants/rs2417888

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