Standard

Creatinine levels

PRORP · rs2415275

Where this position leads

Condition: Kidney Function

rs2415275 Condition: Kidney Function Kidney Function Condition rs2415275 rs2415275 PRORP

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0108 higher (95% confidence interval 0.0083-0.0133); p = 4 × 10−16.

Where it sits Chromosome 14, band 14q13.2 — in an intron of PRORP.

What each result means

A/A Two copies of the version the research linked to Creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Creatinine levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Creatinine levels. This is the starting point the study compared everyone against.
Source

Questions about rs2415275

What is rs2415275?

rs2415275 is a single position in the genome, in or near the PRORP gene. Published research associates it with creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2415275 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs2415275 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2415275 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Creatinine levels (rs2415275). MyGeneLog™. https://www.mygenelog.com/variants/rs2415275

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