1 4322324223221Reads by AI crawlersClaude2ChatGPT2Google · Gemini3Perplexity2Meta AI4Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others21Total43Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,999 Han Chinese ancestry male individuals; replicated in 1,496 Han Chinese ancestry male individuals.
The effect
Each copy of the G allele shifted the measure 0.23 g/L higher (95% confidence interval 0.21-0.25); p = 9 × 10−83.
How common The G allele had a frequency of about 8% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — in an intron of TAP2.
What each result means
G/GTwo copies of the version the research linked to Complement C3 and C4 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Complement C3 and C4 levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Complement C3 and C4 levels. This is the starting point the study compared everyone against.
PLoS genetics · 2012 · PMID 23028341 · open access
Questions about rs241428
What is rs241428?
rs241428 is a single position in the genome, in or near the HLA-DQB gene. Published research associates it with complement c3 and c4 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs241428 linked to?
On MyGeneLog this position is linked to Complement C3 and C4 Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs241428 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs241428 come from?
GWAS Catalog, PLoS Genet 2012, PMID:23028341. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 4322324223221Reads by AI crawlersClaude2ChatGPT2Google · Gemini3Perplexity2Meta AI4Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others21Total43Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Complement C3 and C4 levels (rs241428). MyGeneLog™. https://www.mygenelog.com/variants/rs241428