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Complement C3 and C4 levels

HLA-DQB · rs241428

No connections yet. This position is published on its own. When a condition, drug or sense page here covers it, the links appear on this page automatically.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Complement C3 and C4 levels compared to the general population. (GWAS Catalog, PLoS Genet 2012, PMID:23028341)
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Complement C3 and C4 levels. (GWAS Catalog, PLoS Genet 2012, PMID:23028341)
T/T Published research associates this genotype with typical/baseline likelihood of Complement C3 and C4 levels — no copies of the reported risk allele. (GWAS Catalog, PLoS Genet 2012, PMID:23028341)

Source: GWAS Catalog, PLoS Genet 2012, PMID:23028341

Questions about rs241428

What is rs241428?

rs241428 is a single position in the genome, in or near the HLA-DQB gene. Published research associates it with complement c3 and c4 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs241428 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs241428 come from?

GWAS Catalog, PLoS Genet 2012, PMID:23028341. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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