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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,020 Korculan or Shetland Isles (founder/genetic isolate) individuals.
The effect
Each copy of the A allele shifted the measure 0.242 lower (95% confidence interval 0.18-0.31); p = 6 × 10−13.
How common The A allele had a frequency of about 28% in the people studied.
Where it sits Chromosome 22, band 22q13.1 — in an intron of MGAT3.
What each result means
A/ATwo copies of the version the research linked to Immunoglobulin N-glycan 23 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Immunoglobulin N-glycan 23 levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Immunoglobulin N-glycan 23 levels. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 35332118 · open access
Questions about rs2413592
What is rs2413592?
rs2413592 is a single position in the genome, in or near the MGAT3 gene. Published research associates it with immunoglobulin n-glycan 23 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2413592 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2413592 come from?
GWAS Catalog, Nature communications 2022, PMID:35332118. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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