Standard
Putamen volume
MIR9-2HG · rs2410767
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 37,571 European ancestry individuals; replicated in 341 South East and East Asian ancestry individuals, 769 African American individuals.
The effect
Each copy of the C allele shifted the measure 5.89 z score higher; p = 4 × 10−9.
How common The C allele had a frequency of about 77% in the people studied.
Where it sits Chromosome 5, band 5q14.3 — in an intron of MIR9-2HG.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Putamen volume compared to the general population.
C/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Putamen volume.
G/G
Published research associates this genotype with typical/baseline likelihood of Putamen volume — no copies of the reported risk allele.
Source
Genetic architecture of subcortical brain structures in 38,851 individuals
Satizabal CL,
Adams HHH,
Hibar DP,
White CC,
Knol MJ,
Stein JL,
Scholz M,
Sargurupremraj M,
Jahanshad N,
Roshchupkin GV,
Smith AV,
Bis JC
and 277 more — show all
Jian X,
Luciano M,
Hofer E,
Teumer A,
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van Erp TGM,
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Jönsson EG,
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Uitterlinden AG,
Weinberger DR,
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Fedko IO,
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Nature genetics · 2019 · PMID 31636452
Questions about rs2410767
What is rs2410767?
rs2410767 is a single position in the genome, in or near the MIR9-2HG gene. Published research associates it with putamen volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2410767 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2410767 come from?
GWAS Catalog, Nature genetics 2019, PMID:31636452. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Putamen volume (rs2410767). MyGeneLog™. https://www.mygenelog.com/variants/rs2410767
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