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Who was studied 39,664 European ancestry cases, 119,158 European ancestry controls; replicated in 17,417 European ancestry cases, 13,599 European ancestry controls.
The effect
Each copy of the G allele carried 1.06 times the odds of Lung cancer (conditioned on cigarettes per day) (95% confidence interval 1.044-1.083); p = 4 × 10−11.
How common The G allele had a frequency of about 48% in the people studied.
Where it sits Chromosome 6, band 6q27 — between genes, 0.4 kb from MIR3939.
What each result means
A/ANo copy of the version the research linked to Lung cancer (conditioned on cigarettes per day). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Lung cancer (conditioned on cigarettes per day). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Lung cancer (conditioned on cigarettes per day). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 39366959 · open access
Questions about rs239935
What is rs239935?
rs239935 is a single position in the genome, in or near the near MIR3939 gene. Published research associates it with lung cancer (conditioned on cigarettes per day). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs239935 linked to?
On MyGeneLog this position is linked to Lung Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs239935 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs239935 come from?
GWAS Catalog, Nature communications 2024, PMID:39366959. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Lung cancer (conditioned on cigarettes per day) (rs239935). MyGeneLog™. https://www.mygenelog.com/variants/rs239935