Sensitive

Inflammatory bowel disease

BTNL2 · rs2395158

Where this position leads

Condition: Inflammatory Bowel Disease

rs2395158 Condition: Inflammatory Bowel Disease Inflammatory Bowel Disease Condition rs2395158 rs2395158 BTNL2

What the study found

Who was studied 18,158 European ancestry female cases, 22,345 European ancestry female controls.

The effect Each copy of the G allele carried 0.88 times the odds of Inflammatory bowel disease (95% confidence interval 0.844-0.915); p = 5 × 10−10.

Where it sits Chromosome 6, band 6p21.32 — in a non-coding transcript of BTNL2.

What each result means

A/A No copy of the version the research linked to Inflammatory bowel disease. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Inflammatory bowel disease. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Inflammatory bowel disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2395158

What is rs2395158?

rs2395158 is a single position in the genome, in or near the BTNL2 gene. Published research associates it with inflammatory bowel disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2395158 linked to?

On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs2395158 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2395158 come from?

GWAS Catalog, Inflammatory bowel diseases 2023, PMID:37262302. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Inflammatory bowel disease (rs2395158). MyGeneLog™. https://www.mygenelog.com/variants/rs2395158

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