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Sum neutrophil eosinophil counts

ZBTB16 · rs238914

Where this position leads

Condition: Blood Cell Counts

rs238914 Condition: Blood Cell Counts Blood Cell Counts Condition rs238914 rs238914 ZBTB16

What the study found

Who was studied 170,384 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0259 higher (95% confidence interval 0.019-0.033); p = 2 × 10−12.

How common The A allele had a frequency of about 40% in the people studied.

Where it sits Chromosome 11, band 11q23.2 — in an intron of ZBTB16.

What each result means

A/A Two copies of the version the research linked to Sum neutrophil eosinophil counts. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Sum neutrophil eosinophil counts. That is a smaller link than two copies.
C/C No copy of the version the research linked to Sum neutrophil eosinophil counts. This is the starting point the study compared everyone against.
Source

Questions about rs238914

What is rs238914?

rs238914 is a single position in the genome, in or near the ZBTB16 gene. Published research associates it with sum neutrophil eosinophil counts. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs238914 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs238914 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs238914 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sum neutrophil eosinophil counts (rs238914). MyGeneLog™. https://www.mygenelog.com/variants/rs238914

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