Sensitive

Diabetes / "Sugar"

NUP133 · rs238763

What the study found

Who was studied 16,718 African American or Afro-Caribbean cases, 38,787 African American or Afro-Caribbean controls, 8,910 Hispanic or Latin American cases, 20,404 Hispanic or Latin American controls, 1,007 East Asian ancestry cases, 2,540 East Asian ancestry controls, 80,160 European ancestry cases, 235,508 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0518 higher (95% confidence interval 0.038-0.066); p = 6 × 10−14.

How common The T allele had a frequency of about 51% in the people studied.

Where it sits Chromosome 1, band 1q42.13 — in an intron of NUP133.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Diabetes / "Sugar" — no copies of the reported risk allele.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Diabetes / "Sugar".
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Diabetes / "Sugar" compared to the general population.
Source

Questions about rs238763

What is rs238763?

rs238763 is a single position in the genome, in or near the NUP133 gene. Published research associates it with diabetes / "sugar". A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs238763 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs238763 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Diabetes / "Sugar" (rs238763). MyGeneLog™. https://www.mygenelog.com/variants/rs238763

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