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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 39,121 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0475 higher (95% confidence interval 0.034-0.061); p = 3 × 10−11.
Where it sits Chromosome 9, band 9q21.33 — between genes, 7.9 kb from LINC02834.
What each result means
A/ANo copy of the version the research linked to Bone marrow fat fraction of lumbar vertebra 4. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Bone marrow fat fraction of lumbar vertebra 4. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Bone marrow fat fraction of lumbar vertebra 4. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2025 · PMID 40796918 · open access
Questions about rs2378715
What is rs2378715?
rs2378715 is a single position in the genome, in or near the near LINC02834 gene. Published research associates it with bone marrow fat fraction of lumbar vertebra 4. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2378715 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2378715 come from?
GWAS Catalog, Nature communications 2025, PMID:40796918. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Bone marrow fat fraction of lumbar vertebra 4 (rs2378715). MyGeneLog™. https://www.mygenelog.com/variants/rs2378715