Standard

Triglycerides

PCSK7 · rs236911

Where this position leads

Condition: High Triglycerides

rs236911 Condition: High Triglycerides High Triglycerides Condition rs236911 rs236911 PCSK7

What the study found

Who was studied 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.076 lower; p = 2 × 10−44.

Where it sits Chromosome 11, band 11q23.3 — in an intron of PCSK7.

What each result means

A/A Two copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
C/C No copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
Source

Questions about rs236911

What is rs236911?

rs236911 is a single position in the genome, in or near the PCSK7 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs236911 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

Does having rs236911 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs236911 come from?

GWAS Catalog, Nat Genet 2018, PMID:29507422. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides (rs236911). MyGeneLog™. https://www.mygenelog.com/variants/rs236911

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