Standard

HDL cholesterol

CD36 · rs2366858

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs2366858 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs2366858 rs2366858 CD36

What the study found

Who was studied 7,917 African American individuals, 3,506 Hispanic individuals; replicated in 7,138 African American individuals.

The effect Each copy of the C allele shifted the measure 0.0325 higher; p = 6 × 10−10.

How common The C allele had a frequency of about 17% in the people studied.

Where it sits Chromosome 7, band 7q21.11 — between genes, 31.2 kb from SEMA3C.

What each result means

A/A No copy of the version the research linked to HDL cholesterol. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to HDL cholesterol. That is a smaller link than two copies.
C/C Two copies of the version the research linked to HDL cholesterol. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2366858

What is rs2366858?

rs2366858 is a single position in the genome, in or near the CD36 gene. Published research associates it with hdl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2366858 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs2366858 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2366858 come from?

GWAS Catalog, Am J Hum Genet 2013, PMID:23726366. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

HDL cholesterol (rs2366858). MyGeneLog™. https://www.mygenelog.com/variants/rs2366858

← See all variants