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Varicose veins

near CALM2P1 · rs236597

Where this position leads

Condition: Varicose Veins

rs236597 Condition: Varicose Veins Varicose Veins Condition rs236597 rs236597 near CALM2P1

What the study found

Who was studied 9,577 British ancestry cases, 327,959 British ancestry controls.

The effect Each copy of the T allele shifted the measure 0.117 lower (95% confidence interval 0.084-0.15); p = 2 × 10−12.

How common The T allele had a frequency of about 74% in the people studied.

Where it sits Chromosome 17, band 17q24.3 — between genes, 1.5 kb from CALM2P1.

What each result means

C/C No copy of the version the research linked to Varicose veins. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Varicose veins. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Varicose veins. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs236597

What is rs236597?

rs236597 is a single position in the genome, in or near the near CALM2P1 gene. Published research associates it with varicose veins. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs236597 linked to?

On MyGeneLog this position is linked to Varicose Veins. The research behind each link, and its sources, are set out on that condition page.

Does having rs236597 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs236597 come from?

GWAS Catalog, Circulation 2018, PMID:30566020. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Varicose veins (rs236597). MyGeneLog™. https://www.mygenelog.com/variants/rs236597

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