Standard

Total cholesterol levels

C7orf50 · rs2362529

What the study found

Who was studied 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals; replicated in Up to 319,677 individuals.

The effect Each copy of the T allele shifted the measure 0.0284 mg dl-1 higher (95% confidence interval 0.022-0.035); p = 8 × 10−19.

How common The T allele had a frequency of about 78% in the people studied.

Where it sits Chromosome 7, band 7p22.3 — in an intron of CHLSN.

What each result means

C/C No copy of the version the research linked to Total cholesterol levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Total cholesterol levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Total cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2362529

What is rs2362529?

rs2362529 is a single position in the genome, in or near the C7orf50 gene. Published research associates it with total cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2362529 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2362529 come from?

GWAS Catalog, Nature genetics 2018, PMID:30275531. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Total cholesterol levels (rs2362529). MyGeneLog™. https://www.mygenelog.com/variants/rs2362529

← See all variants