CLEC19A · rs2353663
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,711 Finnish ancestry ever smoker individuals from up to 739 families.
The effect Each copy of the T allele shifted the measure 6.04 higher (95% confidence interval 4.00-8.07); p = 7 × 10−9.
How common The T allele had a frequency of about 6% in the people studied.
Where it sits Chromosome 16, band 16p12.3 — between genes, 3.6 kb from LINC02858.
rs2353663 is a single position in the genome, in or near the CLEC19A gene. Published research associates it with smoking behaviour (maximum cigarettes in a 24 hour period). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Addict Biol 2018, PMID:29532581. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.