Standard

Homocysteine levels

CBS · rs234709

Where this position leads

Condition: Homocysteine Levels

rs234709 Condition: Homocysteine Levels Homocysteine Levels Condition rs234709 rs234709 CBS

What the study found

Who was studied 44,147 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0718 lower (95% confidence interval 0.058-0.086); p = 4 × 10−24.

How common The T allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 21, band 21q22.3 — in an intron of CBS.

What each result means

C/C No copy of the version the research linked to Homocysteine levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Homocysteine levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Homocysteine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs234709

What is rs234709?

rs234709 is a single position in the genome, in or near the CBS gene. Published research associates it with homocysteine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs234709 linked to?

On MyGeneLog this position is linked to Homocysteine Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs234709 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs234709 come from?

GWAS Catalog, Am J Clin Nutr 2013, PMID:23824729. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Homocysteine levels (rs234709). MyGeneLog™. https://www.mygenelog.com/variants/rs234709

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