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Cardiac MRI latent phenotype (Z12_S4)

near RPL29P34 · rs2339798

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 47,740 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0427 lower (95% confidence interval 0.03-0.056); p = 6 × 10⁻¹¹.

Where it sits Chromosome 3, band 3q26.33 — between genes, 3.4 kb from RPL29P34.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cardiac MRI latent phenotype (Z12_S4) compared to the general population.

A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cardiac MRI latent phenotype (Z12_S4).

C/C Published research associates this genotype with typical/baseline likelihood of Cardiac MRI latent phenotype (Z12_S4) — no copies of the reported risk allele.

Source

Hundreds of cardiac MRI traits derived using 3D diffusion autoencoders share a common genetic architecture

Ometto S, Chatterjee S, Vergani AM, Landini A, Sharapov S, Giacopuzzi E, Visconti A, Bianchi E, Santonastaso F, Soda EM, Cisternino F, Pivato CA

and 4 more — show all

Ieva F, Angelantonio ED, Pirastu N, Glastonbury CA

Nature communications · 2026 · PMID 42373625 · open access

Questions about rs2339798

What is rs2339798?

rs2339798 is a single position in the genome, in or near the near RPL29P34 gene. Published research associates it with cardiac mri latent phenotype (z12_s4). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2339798 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2339798 come from?

GWAS Catalog, Nature communications 2026, PMID:42373625. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cardiac MRI latent phenotype (Z12_S4) (rs2339798). MyGeneLog™. https://www.mygenelog.com/variants/rs2339798

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