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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,871 Sardinian (founder/genetic isolate) ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.2 higher (95% confidence interval 0.14-0.25); p = 1 × 10−12.
How common The C allele had a frequency of about 44% in the people studied.
Where it sits Chromosome 6, band 6q15 — in an intron of BACH2.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of CD80 on myeloid Dendritic Cell compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with CD80 on myeloid Dendritic Cell.
T/TPublished research associates this genotype with typical/baseline likelihood of CD80 on myeloid Dendritic Cell — no copies of the reported risk allele.
rs2325259 is a single position in the genome, in or near the BACH2 gene. Published research associates it with cd80 on myeloid dendritic cell. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2325259 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2325259 come from?
GWAS Catalog, Nature genetics 2020, PMID:32929287. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
CD80 on myeloid Dendritic Cell (rs2325259). MyGeneLog™. https://www.mygenelog.com/variants/rs2325259