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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 852 European ancestry cases, 410,350 European ancestry controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 1 × 10−8.
Where it sits Chromosome 6, band 6p25.3 — in the 3′ untranslated region of IRF4.
What each result means
A/ATwo copies of the version the research linked to Lymphocytic leukemia. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Lymphocytic leukemia. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Lymphocytic leukemia. This is the starting point the study compared everyone against.
Nature communications · 2020 · PMID 32887889 · open access
Questions about rs2316515
What is rs2316515?
rs2316515 is a single position in the genome, in or near the IRF4 gene. Published research associates it with lymphocytic leukemia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2316515 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2316515 come from?
GWAS Catalog, Nature communications 2020, PMID:32887889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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