2 4713147222124Reads by AI crawlersClaude1ChatGPT3Google · Gemini1Perplexity4Meta AI7Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others24Total47Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,011 European ancestry cases, 4,250 European ancestry controls; replicated in 1,922 European ancestry cases, 14,124 European ancestry controls.
The effect
Each copy of the G allele carried 1.36 times the odds of Inflammatory bowel disease (95% confidence interval 1.05-1.76); p = 9 × 10−15.
How common The G allele had a frequency of about 69% in the people studied.
Where it sits Chromosome 20, band 20q13.33 — in an intron of ZGPAT.
What each result means
G/GTwo copies of the version the research linked to Inflammatory bowel disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Inflammatory bowel disease. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Inflammatory bowel disease. This is the starting point the study compared everyone against.
rs2315008 is a single position in the genome, in or near the TNFRSF6B gene. Published research associates it with inflammatory bowel disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2315008 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis, Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs2315008 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2315008 come from?
GWAS Catalog, Nat Genet 2008, PMID:18758464. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 4713147222124Reads by AI crawlersClaude1ChatGPT3Google · Gemini1Perplexity4Meta AI7Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others24Total47Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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