0 24191238Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity0Meta AI9Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others8Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls; replicated in 57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls.
The effect
Each copy of the A allele carried 1.07 times the odds of Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) (95% confidence interval 1.04-1.09); p = 1 × 10−9.
How common The A allele had a frequency of about 82% in the people studied.
Where it sits Chromosome 4, band 4q32.1 — in an intron of GUCY1A1.
What each result means
A/ATwo copies of the version the research linked to Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease). This is the starting point the study compared everyone against.
rs2306556 is a single position in the genome, in or near the GUCY1A3 gene. Published research associates it with coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2306556 linked to?
On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs2306556 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2306556 come from?
GWAS Catalog, Nat Genet 2017, PMID:28714975. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 24191238Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity0Meta AI9Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others8Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.