C/CPublished research associates this genotype with typical/baseline likelihood of Tonsillectomy — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Tonsillectomy.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Tonsillectomy compared to the general population.
Nature communications · 2017 · PMID 28928442 · open access
Questions about rs230523
What is rs230523?
rs230523 is a single position in the genome, in or near the NFKB1 gene. Published research associates it with tonsillectomy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs230523 linked to?
On MyGeneLog this position is linked to Tonsillectomy (Throat Infection Susceptibility). The research behind each link, and its sources, are set out on that condition page.
Does having rs230523 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs230523 come from?
GWAS Catalog, Nat Commun 2017, PMID:28928442. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.