Alzheimer's disease or educational attainment (pleiotropy)
OGA · rs2305192
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied (see Lambert 2013 and Okbay 2016).
The effect
Each copy of the T allele shifted the measure 49.1 z score higher; p = 6 × 10−10.
How common The T allele had a frequency of about 65% in the people studied.
Where it sits Chromosome 10, band 10q24.32 — in an intron of OGA.
What each result means
C/CNo copy of the version the research linked to Alzheimer's disease or educational attainment (pleiotropy). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Alzheimer's disease or educational attainment (pleiotropy). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Alzheimer's disease or educational attainment (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs2305192 is a single position in the genome, in or near the OGA gene. Published research associates it with alzheimer's disease or educational attainment (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2305192 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs2305192 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2305192 come from?
GWAS Catalog, GeroScience 2022, PMID:34743297. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Alzheimer's disease or educational attainment (pleiotropy) (rs2305192). MyGeneLog™. https://www.mygenelog.com/variants/rs2305192