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Urokinase plasminogen activator surface receptor levels

PLAUR · rs2302524

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.249 higher (95% confidence interval 0.22-0.28); p = 3 × 10−53.

How common The T allele had a frequency of about 83% in the people studied.

Where it sits Chromosome 19, band 19q13.31 — a missense change in PLAUR.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Urokinase plasminogen activator surface receptor levels — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Urokinase plasminogen activator surface receptor levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Urokinase plasminogen activator surface receptor levels compared to the general population.
Source

Questions about rs2302524

What is rs2302524?

rs2302524 is a single position in the genome, in or near the PLAUR gene. Published research associates it with urokinase plasminogen activator surface receptor levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2302524 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2302524 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urokinase plasminogen activator surface receptor levels (rs2302524). MyGeneLog™. https://www.mygenelog.com/variants/rs2302524

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