2 4532115223224Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity1Meta AI5Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others24Total45Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,624 European ancestry cases, 7,220 European ancestry controls; replicated in 2,215 European ancestry cases, 2,116 European ancestry controls.
The effect
Each copy of the A allele carried 1.30 times the odds of Multiple sclerosis (95% confidence interval 1.14-1.47); p = 3 × 10−10.
How common The A allele had a frequency of about 88% in the people studied.
Where it sits Chromosome 1, band 1p13.1 — in an intron of CD58.
What each result means
A/ATwo copies of the version the research linked to Multiple sclerosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Multiple sclerosis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Multiple sclerosis. This is the starting point the study compared everyone against.
rs2300747 is a single position in the genome, in or near the CD58 gene. Published research associates it with multiple sclerosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2300747 linked to?
On MyGeneLog this position is linked to Multiple Sclerosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs2300747 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2300747 come from?
GWAS Catalog, Nat Genet 2009, PMID:19525953. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 4532115223224Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity1Meta AI5Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others24Total45Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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