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Dehydrogenase/reductase SDR family member 4 levels

ASAH1 · rs2299606

What the study found

Who was studied 2,549 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.428 higher (95% confidence interval 0.38-0.48); p = 1 × 10−61.

How common The A allele had a frequency of about 51% in the people studied.

Where it sits Chromosome 8, band 8p22 — in an intron of ASAH1.

What each result means

A/A Two copies of the version the research linked to Dehydrogenase/reductase SDR family member 4 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Dehydrogenase/reductase SDR family member 4 levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to Dehydrogenase/reductase SDR family member 4 levels. This is the starting point the study compared everyone against.
Source

Questions about rs2299606

What is rs2299606?

rs2299606 is a single position in the genome, in or near the ASAH1 gene. Published research associates it with dehydrogenase/reductase sdr family member 4 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2299606 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2299606 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Dehydrogenase/reductase SDR family member 4 levels (rs2299606). MyGeneLog™. https://www.mygenelog.com/variants/rs2299606

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