1 18122112Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others12Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 51,194 European ancestry cases, 443,383 European ancestry controls; replicated in 17,002 cases, 178,141 controls.
The effect
Each copy of the T allele shifted the measure 0.098 lower (95% confidence interval 0.082-0.114); p = 8 × 10−34.
Where it sits Chromosome 22, band 22q12.3 — inside C1QTNF6.
What each result means
G/GNo copy of the version the research linked to Hypothyroidism. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Hypothyroidism. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Hypothyroidism. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs229540 is a single position in the genome, in or near the C1QTNF6 gene. Published research associates it with hypothyroidism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs229540 linked to?
On MyGeneLog this position is linked to Hypothyroidism. The research behind each link, and its sources, are set out on that condition page.
Does having rs229540 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs229540 come from?
GWAS Catalog, iScience 2022, PMID:36093044. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 18122112Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others12Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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