0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,027 East Asian ancestry cases, 2,708 East Asian ancestry controls; replicated in 3,663 East Asian ancestry cases, 7,548 East Asian ancestry controls.
The effect
Each copy of the C allele carried 1.18 times the odds of Non-cardia gastric cancer (95% confidence interval 1.12-1.26); p = 3 × 10−8.
How common The C allele had a frequency of about 24% in the people studied.
Where it sits Chromosome 6, band 6p21.1 — in an intron of UNC5CL.
What each result means
C/CTwo copies of the version the research linked to Non-cardia gastric cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Non-cardia gastric cancer. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Non-cardia gastric cancer. This is the starting point the study compared everyone against.
rs2294693 is a single position in the genome, in or near the UNC5CL gene. Published research associates it with non-cardia gastric cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2294693 linked to?
On MyGeneLog this position is linked to Non-Cardia Gastric Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs2294693 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2294693 come from?
GWAS Catalog, Gut 2016, PMID:26129866. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Non-cardia gastric cancer (rs2294693). MyGeneLog™. https://www.mygenelog.com/variants/rs2294693