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Height

CHTF18 · rs2294446

Where this position leads

Condition: Height

rs2294446 Condition: Height Height Condition rs2294446 rs2294446 CHTF18

What the study found

Who was studied 5,314,291 European ancestry, Hispanic or Latin American, East Asian ancestry, African ancestry, South Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0095 lower (95% confidence interval 0.0064-0.0126); p = 4 × 10−9.

How common The G allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 16, band 16p13.3 — a synonymous change in CHTF18.

What each result means

A/A No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Height. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2294446

What is rs2294446?

rs2294446 is a single position in the genome, in or near the CHTF18 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2294446 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs2294446 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2294446 come from?

GWAS Catalog, Nature 2022, PMID:36224396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs2294446). MyGeneLog™. https://www.mygenelog.com/variants/rs2294446

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