0 6114Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon1Apple0China (ByteDance, Huawei, Baidu…)0Others4Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.042 lower (95% confidence interval 0.03-0.054); p = 8 × 10−13.
How common The A allele had a frequency of about 87% in the people studied.
Where it sits Chromosome 3, band 3q26.2 — in an intron of SLC2A2.
What ClinVar records
ClassificationBenign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2018-06-23.
ClinVar record 1183692NM_000340.2(SLC2A2):c.775+68T>C
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ATwo copies of the version the research linked to Triglycerides in large LDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Triglycerides in large LDL. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Triglycerides in large LDL. This is the starting point the study compared everyone against.
rs2292622 is a single position in the genome, in or near the SLC2A2 gene. Published research associates it with triglycerides in large ldl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs2292622 affect how medicines work?
SLC2A2 carries pharmacogenomic findings for Metformin. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs2292622 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2292622 come from?
GWAS Catalog, Nature 2024, PMID:38448586. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 6114Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon1Apple0China (ByteDance, Huawei, Baidu…)0Others4Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Triglycerides in large LDL (rs2292622). MyGeneLog™. https://www.mygenelog.com/variants/rs2292622