1 61212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)0Others2Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 4,125 European ancestry cases, 20,464 European ancestry controls.
The effect
Each copy of the C allele carried 1.52 times the odds of Idiopathic pulmonary fibrosis (95% confidence interval 1.36-1.7); p = 4 × 10−13.
How common The C allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 3, band 3p21.31 — a synonymous change in KIF15.
What each result means
C/CTwo copies of the version the research linked to Idiopathic pulmonary fibrosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Idiopathic pulmonary fibrosis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Idiopathic pulmonary fibrosis. This is the starting point the study compared everyone against.
rs2292181 is a single position in the genome, in or near the KIF15 gene. Published research associates it with idiopathic pulmonary fibrosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2292181 linked to?
On MyGeneLog this position is linked to Idiopathic Pulmonary Fibrosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs2292181 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2292181 come from?
GWAS Catalog, Thorax 2022, PMID:35688625. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 61212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)0Others2Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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