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Who was studied 88,192 cases, 162,544 controls; replicated in 34,541 cases, 261,984 controls.
The effect
Each copy of the T allele shifted the measure 0.0531 higher (95% confidence interval 0.04-0.066); p = 4 × 10−16.
How common The T allele had a frequency of about 42% in the people studied.
Where it sits Chromosome 19, band 19q13.2 — in an intron of TGFB1.
What each result means
C/CNo copy of the version the research linked to Coronary artery disease. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Coronary artery disease. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Circulation research · 2018 · PMID 29212778 · open access
Questions about rs2288874
What is rs2288874?
rs2288874 is a single position in the genome, in or near the B9D2 gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2288874 linked to?
On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs2288874 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2288874 come from?
GWAS Catalog, Circ Res 2017, PMID:29212778. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 242721327Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity2Meta AI7Microsoft · Copilot2Amazon1Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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