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Retinal vascular caliber

FUT2 · rs2287921

What the study found

Who was studied 15,358 European ancestry individuals; replicated in 6,652 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 2.1 um lower (95% confidence interval 1.71-2.49); p = 2 × 10−25.

How common The T allele had a frequency of about 47% in the people studied.

Where it sits Chromosome 19, band 19q13.33 — in an intron of RASIP1.

What each result means

C/C No copy of the version the research linked to Retinal vascular caliber. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Retinal vascular caliber. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Retinal vascular caliber. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2287921

What is rs2287921?

rs2287921 is a single position in the genome, in or near the FUT2 gene. Published research associates it with retinal vascular caliber. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2287921 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2287921 come from?

GWAS Catalog, PLoS Genet 2010, PMID:21060863. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Retinal vascular caliber (rs2287921). MyGeneLog™. https://www.mygenelog.com/variants/rs2287921

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