Sensitive

Carpal tunnel syndrome

MKNK2 · rs2287002

Where this position leads

Condition: Carpal Tunnel Syndrome

rs2287002 Condition: Carpal Tunnel Syndrome Carpal Tunnel Syndrome Condition rs2287002 rs2287002 MKNK2

What the study found

Who was studied 48,843 European ancestry cases, 1,190,837 European ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 2 × 10−9.

How common The A allele had a frequency of about 23% in the people studied.

Where it sits Chromosome 19, band 19p13.3 — in the 3′ untranslated region of MKNK2.

What each result means

A/A Two copies of the version the research linked to Carpal tunnel syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Carpal tunnel syndrome. That is a smaller link than two copies.
G/G No copy of the version the research linked to Carpal tunnel syndrome. This is the starting point the study compared everyone against.
Source

Questions about rs2287002

What is rs2287002?

rs2287002 is a single position in the genome, in or near the MKNK2 gene. Published research associates it with carpal tunnel syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2287002 linked to?

On MyGeneLog this position is linked to Carpal Tunnel Syndrome. The research behind each link, and its sources, are set out on that condition page.

Does having rs2287002 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2287002 come from?

GWAS Catalog, Nature communications 2022, PMID:35332129. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Carpal tunnel syndrome (rs2287002). MyGeneLog™. https://www.mygenelog.com/variants/rs2287002

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