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Inter-alpha-trypsin inhibitor heavy chain H1 levels

ITIH1 · rs2286798

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.75 higher (95% confidence interval 0.73-0.77).

How common The A allele had a frequency of about 64% in the people studied.

Where it sits Chromosome 3, band 3p21.1 — in an intron of ITIH1.

What each result means

A/A Two copies of the version the research linked to Inter-alpha-trypsin inhibitor heavy chain H1 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Inter-alpha-trypsin inhibitor heavy chain H1 levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to Inter-alpha-trypsin inhibitor heavy chain H1 levels. This is the starting point the study compared everyone against.
Source

Questions about rs2286798

What is rs2286798?

rs2286798 is a single position in the genome, in or near the ITIH1 gene. Published research associates it with inter-alpha-trypsin inhibitor heavy chain h1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2286798 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2286798 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Inter-alpha-trypsin inhibitor heavy chain H1 levels (rs2286798). MyGeneLog™. https://www.mygenelog.com/variants/rs2286798

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