Standard

Glucose levels (adjusted for time of day)

TENT5C · rs2282456

What the study found

Who was studied 387,790 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0206 higher (95% confidence interval 0.015-0.026); p = 2 × 10−12.

How common The A allele had a frequency of about 31% in the people studied.

Where it sits Chromosome 1, band 1p12 — in the 3′ untranslated region of TENT5C.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Glucose levels (adjusted for time of day) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Glucose levels (adjusted for time of day).
G/G Published research associates this genotype with typical/baseline likelihood of Glucose levels (adjusted for time of day) — no copies of the reported risk allele.
Source

Questions about rs2282456

What is rs2282456?

rs2282456 is a single position in the genome, in or near the TENT5C gene. Published research associates it with glucose levels (adjusted for time of day). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2282456 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2282456 come from?

GWAS Catalog, Nature communications 2026, PMID:42173832. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Glucose levels (adjusted for time of day) (rs2282456). MyGeneLog™. https://www.mygenelog.com/variants/rs2282456

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