Standard

Triglycerides

MEIS1 · rs2280334

Where this position leads

Condition: High Triglycerides

rs2280334 Condition: High Triglycerides High Triglycerides Condition rs2280334 rs2280334 MEIS1

What the study found

Who was studied 265,204 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.017 higher; p = 5 × 10−8.

Where it sits Chromosome 2, band 2p14 — in an intron of MEIS1.

What each result means

C/C No copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2280334

What is rs2280334?

rs2280334 is a single position in the genome, in or near the MEIS1 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2280334 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

Does having rs2280334 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2280334 come from?

GWAS Catalog, Nat Genet 2018, PMID:29507422. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides (rs2280334). MyGeneLog™. https://www.mygenelog.com/variants/rs2280334

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