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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,083,151 European ancestry individuals; replicated in 287,239 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.00753 lower (95% confidence interval 0.0054-0.0096); p = 1 × 10−12.
How common The C allele had a frequency of about 25% in the people studied.
Where it sits Chromosome 3, band 3p21.1 — in an intron of STIMATE.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Well-being spectrum (multivariate analysis) compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Well-being spectrum (multivariate analysis).
T/TPublished research associates this genotype with typical/baseline likelihood of Well-being spectrum (multivariate analysis) — no copies of the reported risk allele.
rs2276825 is a single position in the genome, in or near the STIMATE-MUSTN1 gene. Published research associates it with well-being spectrum (multivariate analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2276825 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2276825 come from?
GWAS Catalog, Nat Genet 2019, PMID:30643256. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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