1 4632118223222Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity1Meta AI8Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total46Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 44,147 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0542 lower (95% confidence interval 0.037-0.072); p = 2 × 10−10.
How common The T allele had a frequency of about 21% in the people studied.
Where it sits Chromosome 1, band 1q43 — in an intron of MTR.
What ClinVar records
ClassificationBenign; criteria provided, single submitter (1 of 4 stars, 1 submitter), last evaluated 2018-10-01.
ClinVar record 1282022NM_000254.3(MTR):c.2775+157G>T
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
G/GNo copy of the version the research linked to Homocysteine levels. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Homocysteine levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Homocysteine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
The American journal of clinical nutrition · 2013 · PMID 23824729
Questions about rs2275565
What is rs2275565?
rs2275565 is a single position in the genome, in or near the MTR gene. Published research associates it with homocysteine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2275565 linked to?
On MyGeneLog this position is linked to Homocysteine Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs2275565 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2275565 come from?
GWAS Catalog, Am J Clin Nutr 2013, PMID:23824729. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 4632118223222Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity1Meta AI8Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total46Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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