Standard

Eosinophil count

C11orf65 · rs227051

Where this position leads

Condition: Blood Cell Counts

rs227051 Condition: Blood Cell Counts Blood Cell Counts Condition rs227051 rs227051 C11orf65

What the study found

Who was studied 583,850 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 9 × 10−35.

How common The A allele had a frequency of about 54% in the people studied.

Where it sits Chromosome 11, band 11q22.3 — in an intron of C11orf65.

What each result means

A/A Two copies of the version the research linked to Eosinophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Eosinophil count. That is a smaller link than two copies.
G/G No copy of the version the research linked to Eosinophil count. This is the starting point the study compared everyone against.
Source

Questions about rs227051

What is rs227051?

rs227051 is a single position in the genome, in or near the C11orf65 gene. Published research associates it with eosinophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs227051 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs227051 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs227051 come from?

GWAS Catalog, Cell 2020, PMID:32888493. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Eosinophil count (rs227051). MyGeneLog™. https://www.mygenelog.com/variants/rs227051

← See all variants