Hypersensitivity reaction to iodinated contrast media
near C6orf15 · rs2270190
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 123 Japanese ancestry cases, 8,380 Japanese ancestry controls.
The effect
Each copy of the G allele carried 2.52 times the odds of Hypersensitivity reaction to iodinated contrast media (95% confidence interval 1.86-3.4); p = 3 × 10−8.
How common The G allele had a frequency of about 10% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — between genes, 0.2 kb from C6orf15.
What each result means
A/ANo copy of the version the research linked to Hypersensitivity reaction to iodinated contrast media. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Hypersensitivity reaction to iodinated contrast media. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Hypersensitivity reaction to iodinated contrast media. That is the strongest link of the three results. A link in a study is not a diagnosis.
International heart journal · 2026 · PMID 42732936
Questions about rs2270190
What is rs2270190?
rs2270190 is a single position in the genome, in or near the near C6orf15 gene. Published research associates it with hypersensitivity reaction to iodinated contrast media. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2270190 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2270190 come from?
GWAS Catalog, International heart journal 2026, PMID:42732936. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Hypersensitivity reaction to iodinated contrast media (rs2270190). MyGeneLog™. https://www.mygenelog.com/variants/rs2270190