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Bioavailable testosterone levels

FMO3 · rs2266782

What the study found

Who was studied 188,507 European ancestry women.

The effect Each copy of the A allele shifted the measure 0.0161 higher (95% confidence interval 0.011-0.021); p = 3 × 10−11.

How common The A allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 1, band 1q24.3 — a missense change in FMO3.

What each result means

A/A Two copies of the version the research linked to Bioavailable testosterone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Bioavailable testosterone levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Bioavailable testosterone levels. This is the starting point the study compared everyone against.
Source

Questions about rs2266782

What is rs2266782?

rs2266782 is a single position in the genome, in or near the FMO3 gene. Published research associates it with bioavailable testosterone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2266782 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2266782 come from?

GWAS Catalog, Nature medicine 2020, PMID:32042192. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Bioavailable testosterone levels (rs2266782). MyGeneLog™. https://www.mygenelog.com/variants/rs2266782

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