WBP1L · rs2253950
Where this position leads
Condition: Waist Circumference
What the study found
Who was studied 219,872 British ancestry women.
The effect Each copy of the A allele shifted the measure 0.0223 lower (95% confidence interval 0.016-0.028); p = 1 × 10−12.
Where it sits Chromosome 10, band 10q24.32 — in an intron of WBP1L.
rs2253950 is a single position in the genome, in or near the WBP1L gene. Published research associates it with waist circumference adjusted for body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Waist Circumference. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Scientific reports 2021, PMID:34021172. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Waist circumference adjusted for body mass index (rs2253950). MyGeneLog™. https://www.mygenelog.com/variants/rs2253950