KRT24 · rs2253717
Where this position leads
Condition: Asthma
What the study found
Who was studied 46,802 European ancestry cases, 347,481 European ancestry controls; replicated in 23,948 European and unknown ancestry cases, 118,538 European and unknown ancestry controls.
The effect Each copy of the G allele carried 1.04 times the odds of Asthma (95% confidence interval 1.03-1.06); p = 3 × 10−10.
How common The G allele had a frequency of about 72% in the people studied.
Where it sits Chromosome 17, band 17q21.2 — between genes, 7 kb from KRT223P.
rs2253717 is a single position in the genome, in or near the KRT24 gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, The European respiratory journal 2019, PMID:31619474. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Asthma (rs2253717). MyGeneLog™. https://www.mygenelog.com/variants/rs2253717