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IgE levels

FCER1A · rs2251746

What the study found

Who was studied 1,530 European ancesrty individuals; replicated in 9,769 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 19.2 % lower; p = 2 × 10−20.

How common The C allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 1, band 1q23.2 — inside FCER1A.

What each result means

C/C Two copies of the version the research linked to IgE levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to IgE levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to IgE levels. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs2251746

What is rs2251746?

rs2251746 is a single position in the genome, in or near the FCER1A gene. Published research associates it with ige levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs2251746?

Subjects that appear in the title or abstract of the same papers as this rsID include allergies (6 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs2251746 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2251746 come from?

GWAS Catalog, PLoS Genet 2008, PMID:18846228. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

IgE levels (rs2251746). MyGeneLog™. https://www.mygenelog.com/variants/rs2251746

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