Standard

Age at first sexual intercourse

BLK · rs2248699

Where this position leads

Condition: Age at First Sexual Intercourse

rs2248699 Condition: Age at First Sexual Intercourse Age at First Sexual Intercourse Condition rs2248699 rs2248699 BLK

What the study found

Who was studied 59,357 British ancestry males, 66,310 British ancestry females.

The effect Each copy of the G allele shifted the measure 0.0241 higher (95% confidence interval 0.017-0.032); p = 4 × 10−10.

How common The G allele had a frequency of about 50% in the people studied.

Where it sits Chromosome 8, band 8p23.1 — in an intron of BLK.

What each result means

A/A No copy of the version the research linked to Age at first sexual intercourse. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Age at first sexual intercourse. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Age at first sexual intercourse. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2248699

What is rs2248699?

rs2248699 is a single position in the genome, in or near the BLK gene. Published research associates it with age at first sexual intercourse. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2248699 linked to?

On MyGeneLog this position is linked to Age at First Sexual Intercourse. The research behind each link, and its sources, are set out on that condition page.

Does having rs2248699 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2248699 come from?

GWAS Catalog, Nat Genet 2016, PMID:27089180. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Age at first sexual intercourse (rs2248699). MyGeneLog™. https://www.mygenelog.com/variants/rs2248699

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